Prof. Rossjohn is an NHMRC Australia Fellow at Monash University. Rossjohn has provided profound insight into T-cell biology, defining the basis of key immune recognition events by T-cells. He has used structural biology to explain pre-T-cell receptor (TCR) self-association in T-cell development, and how the TCR specifically recognises polymorphic Human Leukocyte Antigen (HLA) molecules in the context of viral immunity and aberrant T-cell reactivity. He has unearthed mechanisms of HLA polymorphism impacting on drug and food hypersensitivities, as well as Natural Killer cell receptor recognition. He has pioneered our understanding of lipid-based immunity by the innate Natural Killer T-cells, as well as MAIT cell recognition of vitamin B metabolites.