Molecular insights into the capability of the MR1 molecule to display host-derived metabolites for T cell surveillance (#101)

5:00 PM

Wael Awad

Proximal tubule CD1d and natural killer T-cells in acute cardiorenal syndrome (#102)

5:00 PM

Kevin G Burfeind

DEVELOPMENT OF REJECTION-RESISTANT ALLOGENEIC CAR-NKT CELL THERAPY FOR CD19-POSITIVE B CELL MALIGNANCIES  (#103)

5:00 PM

Kshiti Dholakia

High throughput discovery approaches identify human self-metabolites of several chemical classes as antigens for MAIT cells (#104)

5:00 PM

Iria Gomez-Tourino

Activated MAIT cells drive fibrosis in primary sclerosing cholangitis in a SPARC dependent manner (#105)

5:00 PM

Florencia Gutierrez

Analysis of collaborative cross mouse strains to identify genes differentially involved in MAIT versus NKT cell thymic development (#106)

5:00 PM

Emi Ito

Synaptotagmin 1 and Synaptotagmin 7 promote MR1-mediated presentation of Mycobacterium tuberculosis antigens (#107)

5:00 PM

Se-Jin Kim

Mutations outside the MR1 antigen binding groove differentially inhibit presentation of exogenous antigens (#108)

5:00 PM

Corinna A Kulicke

Development of a sensitive, scalable assay for MR1-bound 5-OP-RU (#109)

5:00 PM

Martin Lett

Investigating the molecular basis by which antigens are loaded onto different MR1 variants (#110)

5:00 PM

Victoria Letoga

Discovering isoform-specific lipidomic signatures associated with human CD1 proteins (#111)

5:00 PM

Shuqi Li

Understanding the Molecular Mechanism of Recognition of Bacteroides fragilis produced glycosphingolipids by Natural Killer T (NKT) cell Receptors (#112)

5:00 PM

Vasudha Maddali

Metabolomic analysis of mammalian-derived MR1-ligands (#113)

5:00 PM

Edward J Mathias

Probing CD1d mediated lipid specific iNKT interactions in solution (#114)

5:00 PM

Uri Z Miles

Identification of self-metabolites as MR1 ligands and autoantigens in Type 1 diabetes (#115)

5:00 PM

Lucía Mosquera-Ferreiro

Allelic variation of MR1 shapes its antigen repertoire and presentation capacity (#116)

5:00 PM

Adam G Nelson

TCR-dependent MAIT cell activation controls visual function (#117)

5:00 PM

Kensuke Shibata

NAADP-mediated endosomal calcium signaling enables MR1 presentation of Mycobacterium tuberculosis (#118)

5:00 PM

Allison Tammen

Multimodal profiling of phosphomycoketide-reactive γδ T cells in BCG-vaccinated South African infants (#119)

5:00 PM

Tori Tappen

Deciphering the molecular basis of headless lipid recognition by NKT cells   (#120)

5:00 PM

Praveena Thirunavukkarasu

Crohn’s disease-Associated Invariant T (CAIT) cells from Crohn’s disease patients are activated by hydrophobic antigens in human ileum (#121)

5:00 PM

Ildiko Van Rhijn

Allogeneic NKT Cells Expressing a CD19-specific CAR in Patients with Relapsed or Refractory B cell Malignancies: an Interim Analysis (#130)

5:02 PM

Leonid Metelitsa